Publicly available datasets developed in 2024. Datasets developed as part of the Row Fogo Centre for Research into Ageing and the Brain in 2024. Expand the following shortcuts to read more about the datasets and access related links. Normal reference T1-weighted MR images for the brain at ages 65-70 and 75-80 years Link to resource in Edinburgh Datashare Data Creators Armitage, Paul, Chappell, Francesca, MacLullich, Alasdair, Shenkin, Susan, Wardlaw, Joanna M. Description As part of an early effort to provide reference images of healthy ageing in older subjects, two T1-weighted MR imaging templates were created as described by Farrell et al. in a previous publication [1]. Briefly, brain T1-weighted MRI from 79 community-dwelling older individuals, previously grouped in two age intervals, were aligned using affine registration. The images were considered representative of the normal human brain at ages 65-70 and 75-80 years. The individuals providing the data were considered normal as determined by a medical and psychiatric records as well as medical and cognitive assessment. The templates were tested by two neuroradiologists during routine interpretation of MR and CT brain images. Here, we provide the template files in nifti-1 format, to be used in further research. Citation Armitage, Paul; Chappell, Francesca; MacLullich, Alasdair; Shenkin, Susan; Wardlaw, Joanna M.. (2024). Normal reference T1-weighted MR images for the brain at ages 65-70 and 75-80 years, [dataset]. University of Edinburgh. Brain Research Imaging Centre. Centre for Clinical Brain Sciences. https://doi.org/10.7488/ds/7763. Large intracranial artery regions in MRI head templates for calcium segmentation Link to resource in Edinburgh Datashare Data Creators Jin, Benjamin, Valdés Hernández, Maria del C, Mair, Grant Description We defined five rectangular regions of interest (ROIs) around large intracranial arteries on two T1-weighted MRI templates of the head from Armitage et al., which are available online from the Edinburgh DataShare at https://doi.org/10.7488/ds/7763. The five ROIs are the following: Vertebral arteries from the foramen magnum up to the termination. Basilar artery from the joining of the vertebral arteries to the Circle of Willis. Internal carotid artery, the cavernous segment up to the Circle of Willis. The M1 segment of the left middle cerebral artery (MCA). The M1 segment of the right MCA. The MRI templates are age-specific for ranges 65-70 and 75-80. We use these approximate regions for subsequent precise segmentation and quantification of intracranial arterial calcification in co-registered CT scans. Citation Jin, Benjamin; Valdés Hernández, Maria del C; Mair, Grant. (2024). Large intracranial artery regions in MRI head templates for calcium segmentation, [dataset]. University of Edinburgh. Brain Research Imaging Centre. Centre for Clinical Brain Sciences. https://doi.org/10.7488/ds/7765. Expand all Collapse all This article was published on 2024-08-27