PhD Opportunities

Race Against Dementia: All Hands Team Vascular

Vascular causes of dementia are common. Cerebral small vessel disease (cSVD) is the leading cause of vascular cognitive impairment (VCI) and vascular dementia (VaD) including in mixed dementias with Alzheimer’s disease. Despite causing up to 45% of dementias, research and established treatments for vascular causes of dementia are lacking. Race Against Dementia (RAD): Team Vascular - Prevention and Treatment of Vascular Cognitive Impairment and Dementia is a cross-disciplinary team working together to prevent and treat vascular causes of cognitive impairment and dementia, with expertise in cSVD, Alzheimer’s disease and dementia, clinical research including trials, discovery science, and data science including experimental validity, literature and drug data interrogation. The Team comprises four interconnected workstreams: LACI-Cog, a pilot trial in patients with cognitive decline; LACI-Rat, conducting randomised trials in preclinical rodent models; LACI-Hunt, to develop efficient methods of searching for new drug targets and drugs; and LACI-Ignite, to advocate for the importance of vascular causes of dementia, foster awareness, and promote interest amongst early career and senior researchers, funders and policy-makers.

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