Publications

Find out about our recent scientific publications.

  Publications 2024

Zhao, M., Li, Y., Han, X., Li, C., Wang, P., Wang, J., Hou, T., Wang, Y., Cong, L., Wardlaw, J. M., Launer, L. J., Song, L., Du, Y., & Qiu, C. (2024). Association of enlarged perivascular spaces with cognitive function in dementia-free older adults: A population-based study. Alzheimer's & dementia (Amsterdam, Netherlands), 16(3), e12618. https://doi.org/10.1002/dad2.12618 

Viengkhou, B., Hayashida, E., McGlasson, S., Emelianova, K., Forbes, D., Wiseman, S., Wardlaw, J., Verdillo, R., Irani, S. R., Duffy, D., Piehl, F., Loo, L., Pagenstecher, A., Neely, G. G., Crow, Y. J., Campbell, I. L., Hunt, D. P. J., & Hofer, M. J. (2024). The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies. Immunity, 57(7), 1696–1709.e10. https://doi.org/10.1016/j.immuni.2024.05.017 

Zhang, J., Chen, H., Wang, J., Huang, Q., Xu, X., Wang, W., Xu, W., Guan, Y., Liu, J., Wardlaw, J. M., Deng, Y., Xie, F., & Li, B. (2024). Linking white matter hyperintensities to regional cortical thinning, amyloid deposition, and synaptic density loss in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(6), 3931–3942. https://doi.org/10.1002/alz.13845 

Page, D., Buchanan, C. R., Moodie, J. E., Harris, M. A., Taylor, A., Valdés Hernández, M., Muñoz Maniega, S., Corley, J., Bastin, M. E., Wardlaw, J. M., Russ, T. C., Deary, I. J., & Cox, S. R. (2024). Examining the neurostructural architecture of intelligence: The Lothian Birth Cohort 1936 study. Cortex; a journal devoted to the study of the nervous system and behavior, 178, 269–286. https://doi.org/10.1016/j.cortex.2024.06.007 

Tranfa, M., Lorenzini, L., Collij, L. E., Vállez García, D., Ingala, S., Pontillo, G., Pieperhoff, L., Maranzano, A., Wolz, R., Haller, S., Blennow, K., Frisoni, G., Sudre, C. H., Chételat, G., Ewers, M., Payoux, P., Waldman, A., Martinez-Lage, P., Schwarz, A. J., Ritchie, C. W., … Barkhof, F. (2024). Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter Microstructure. Annals of clinical and translational neurology, 11(6), 1541–1556. https://doi.org/10.1002/acn3.52071 

Baranyi, G., Buchanan, C. R., Conole, E. L. S., Backhouse, E. V., Maniega, S. M., Hernandez, M. V., Bastin, M. E., Wardlaw, J., Deary, I. J., Cox, S. R., & Pearce, J. (2023). Life-course neighbourhood deprivation and brain structure in older adults: The Lothian Birth Cohort 1936. medRxiv : the preprint server for health sciences, 2023.04.13.23288523. https://doi.org/10.1101/2023.04.13.23288523 

Zhang, J., Chen, H., Wang, J., Huang, Q., Xu, X., Wang, W., Xu, W., Guan, Y., Liu, J., Wardlaw, J. M., Deng, Y., Xie, F., & Li, B. (2024). Linking white matter hyperintensities to regional cortical thinning, amyloid deposition, and synaptic density loss in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(6), 3931–3942. https://doi.org/10.1002/alz.13845 

Meinel, T. R., Wardlaw, J. M., & Kent, D. M. (2024). Is Incidentally Discovered Covert Cerebrovascular Disease Ignorable?. JAMA neurology, 81(5), 437–438. https://doi.org/10.1001/jamaneurol.2023.5456

Clancy, U., Kancheva, A. K., Valdés Hernández, M. D. C., Jochems, A. C. C., Muñoz Maniega, S., Quinn, T. J., & Wardlaw, J. M. (2024). Imaging Biomarkers of VCI: A Focused Update. Stroke, 55(4), 791–800. https://doi.org/10.1161/STROKEAHA.123.044171 

Hwai, S. W. C., Wardlaw, J. M., Williams, A., & Doubal, F. N. (2024). What matters to people and families affected by cerebral small vessel disease (SVD)? A qualitative grounded theory investigation. Cerebral circulation - cognition and behavior, 6, 100202. https://doi.org/10.1016/j.cccb.2024.100202 

Wardlaw, J. M., Chabriat, H., de Leeuw, F. E., Debette, S., Dichgans, M., Doubal, F., Jokinen, H., Katsanos, A. H., Ornello, R., Pantoni, L., Pasi, M., Pavlovic, A. M., Rudilosso, S., Schmidt, R., Staals, J., Taylor-Rowan, M., Hussain, S., & Lindgren, A. G. (2024). European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke. European stroke journal, 9(1), 5–68. https://doi.org/10.1177/23969873231219416 

Moodie, J. E., Harris, S. E., Harris, M. A., Buchanan, C. R., Davies, G., Taylor, A., Redmond, P., Liewald, D., Del C Valdés Hernández, M., Shenkin, S., Russ, T. C., Muñoz Maniega, S., Luciano, M., Corley, J., Stolicyn, A., Shen, X., Steele, D., Waiter, G., Sandu-Giuraniuc, A., Bastin, M. E., … Cox, S. R. (2023). General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning. bioRxiv : the preprint server for biology, 2023.03.16.532915. https://doi.org/10.1101/2023.03.16.532915 

Moodie, J. E., Harris, S. E., Harris, M. A., Buchanan, C. R., Davies, G., Taylor, A., Redmond, P., Liewald, D., Del C Valdés Hernández, M., Shenkin, S., Russ, T. C., Muñoz Maniega, S., Luciano, M., Corley, J., Stolicyn, A., Shen, X., Steele, D., Waiter, G., Sandu-Giuraniuc, A., Bastin, M. E., … Cox, S. R. (2023). General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning. bioRxiv : the preprint server for biology, 2023.03.16.532915. https://doi.org/10.1101/2023.03.16.532915 

  Publications 2023

Vacek, Mair et al (2023) Evaluating artificial intelligence software for delineating hemorrhage extent on CT brain imaging in stroke

Burke, Engelmann et al (2023) An Open-Source Deep Learning Algorithm for Efficient and Fully Automatic Analysis of the Choroid in Optical Coherence Tomography

Dehsarvi, Warsity et al (2023) Characterising the neurobiological mechanisms of action of exercise and cognitive behavioural interventions for rheumatoid arthritis fatigue: an MRI brain study

Sri, Greenstein et al (2023) A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia

Kopczak, Stringer et al (2023) Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial 

Sennfält et al (2023) Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques

Alzahrani et al (2023) Assessing Brain Tissue Viability on Nonenhanced Computed Tomography After Ischemic Stroke

Aribisala et al. (2023) Sleep quality, perivascular spaces and brain health markers in ageing - A longitudinal study in the Lothian Birth Cohort 1936

Boots et al. (2023) Shaping the risk for late-life neurodegenerative disease: A systematic review on prenatal risk factors for Alzheimer’s disease-related volumetric brain biomarkers

Clancy et al (2023) Are neuropsychiatric symptoms a marker of small vessel disease progression in older adults? Evidence from the Lothian Birth Cohort 1936

Clancy et al. (2023) Neuropsychiatric symptoms as a sign of small vessel disease progression in cognitive impairment

Duering et al. (2023) Neuroimaging standards for research into small vessel disease—advances since 2013

Exalto et al. (2023) Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke

Gibson et al. (2023) Towards equality: gender representation at the Royal College of Radiologists’ Annual Scientific Meeting 2014-2021

Humphreys and Hernandez (2023) Impact of polycyclic aromatic hydrocarbon exposure on cognitive function and neurodegeneration in humans: A systematic review and meta-analysis

Kopczak et al. (2023) The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial

Lam et al (2022) The global burden of cerebral small vessel disease in low- and middle-income countries - a systematic review and meta-analysis

Liebeskind and Wardlaw (2023) Imaging Advances in Stroke: Use of Advanced Neurovascular Imaging or Disruptive Innovation With Artificial Intelligence?

Rudilosso et al. (2023) Blood-brain barrier leakage hotspots collocating with brain lesions due to sporadic and monogenic small vessel disease

Sáenz de Villaverde Cortabarría et al. (2023) Paranasal sinuses opacification on magnetic resonance imaging in relation to brain health in sporadic small vessel disease - Systematic review and pilot analysis

Schreiber et al. (2023) Brain Vascular Health in ALS Is Mediated through Motor Cortex Microvascular Integrity

Sennfalt et al. (2023) Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques

Siedlinski et al. (2023) Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

Valdes Hernandez et al. (2023) Paranasal sinus occupancy assessed from magnetic resonance images-associations with clinical indicators in patients with systemic lupus erythematosus

Wang et al. (2023) Baseline brain imaging signs in patients with ischaemic stroke by the presence of atrial fibrillation: the ENCHANTED trial

Wardlaw et al. (2023) Even more benefit with endovascular treatment for patients with acute ischaemic stroke: MR CLEAN-LATE

Wardlaw et al. (2023) Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel DiseaseThe Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial

Whittington et al. (2023) Noninvasive In Vivo Thrombus Imaging in Patients With Ischemic Stroke or Transient Ischemic Attack

 

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